Bleach + ammonia: never
This combination can release toxic chloramine gases. Ammonia may be present in products you do not immediately think of as “ammonia cleaner,” so read labels rather than guessing from the product name.
Bleach + vinegar or other acids: never
Acidifying bleach can release chlorine gas. Vinegar is an acid, as are many toilet-bowl, rust-removal and descaling products. Do not combine them with bleach.
Bleach + another cleaner or disinfectant: do not experiment
The CDC’s advice is broader than a short list of famous combinations: never mix household bleach or disinfectants with other cleaners or disinfectants. Follow the product label instead of creating your own mixture.
Why rinsing between products matters
If you decide to use a different cleaner after the first one, remove the first product completely and rinse the surface as directed. Residue left behind can still react with a second chemical.
Safer habits for everyday cleaning
- Read the entire product label before use.
- Keep products in their original labeled containers.
- Ventilate the room when the label calls for it.
- Wear gloves or eye protection when directed.
- Do not mix products to create a “stronger” solution.
- Store chemicals away from children and pets.
Cleaning and disinfecting are not the same thing
CDC guidance notes that in many everyday household situations, cleaning with soap and water is enough to remove dirt and many germs. Disinfecting may be appropriate in particular situations, but it should be done using an appropriate product according to its label — not by combining chemicals.